Endocrine Abstracts

Purpose: Androgens promote early follicular development and granulosa cell proliferation by augmenting follicle-stimulating hormone (FSH) receptor expression in granulosa cells. Several retrospective studies have evaluated the association between basal androgen concentrations and follicular development in women undergoing ovarian stimulation for in vitro fertilization (IVF) with conflicting results. The aim of this study was to investigate whether basal androgen concentrations...

Introduction: The role of thyroxine (T4) during embryo development is recognised as crucial. The research question of this study was if embryo quality and reproductive outcomes after IVF are affected by maternal thyroid function and/or thyroid auto-immunity (TAI).Methods/design: We conducted a prospective study (ThyrART), assessing embryo quality and reproductive outcome of women undergoing ovarian stimulation with a flexible GnRH-antagonist p...

Introduction: The evidence of the impact of OS for IVF and thyroid function or autoimmunity is inconclusive, based mainly on assessments just before and after OS. The aim of this study was to closely monitor the changes on thyroid function and autoimmunity throughout OS for IVF.Description of methods/designs: In a prospective, interventional study, a flexible GnRH-antagonist protocol was applied to 42 women undergoing IVF ((classic or ICSI), with initiat...

PurposeRadioactive iodine (RAI) is frequently used as adjuvant therapy in patients with differentiated thyroid cancer (DTC). However, its effect on ovarian reserve has not been fully elucidated, with studies yielding inconsistent results. The aim of this study was to systematically review and meta-analyze the best available evidence regarding the effect of RAI on ovarian reserve in premenopausal women with DTC.Methods<p class="...